Programme
Dates of the meeting: September 8th & 9th 2021
Live Programme (4 hours each day for 2 days):
The live talk sessions and Round Tables discussions will take place via Zoom. Posters and Networking by gather.town
Start and end times:
- 6:00 AM-10:00AM San Francisco,
- 9:00AM-1:00PM New York,
- 2:00-6:00PM London,
- 3:00-7:00 PM Berlin,
- 6:30 PM-10:30PM Mumbai,
- 10:00PM-2:00AM Tokyo,
- 11:00PM-3:00AM Sydney (note end times in Tokyo and Sydney are +1 day)
Talk Sessions:
All talks were selected from submitted abstracts and are typically (15 mins + 5 mins for questions). All talks will be hosted live via Zoom Webinar.
September 8th
| Time (UK) | Speaker | Title |
|---|---|---|
| 1.00 PM | Poster presenters at their posters (optional) – gather.town | |
| 1.50 PM | Andrew Carter, Richard McKenney | Welcome |
Session 1: Dynein and kinesin
| Time (UK) | Speaker | Title |
|---|---|---|
| 2.00 PM | Anne Straube | Co-operation of KIF1C and dynein in bidirectional cargo transport |
| 2.20 PM | John Canty | In vitro reconstitution defines mitochondrial TRAK cargo adaptors as activators of dynein and kinesin |
| 2.40 PM | Reto Gassman | JIP3 recruits dynein and kinesin-1 to regulate bi-directional organelle transport in neurons |
| 3.00 PM | Ennio d’Amico | Conformational changes of the activating adaptor Spindly underlies Dynein regulation at the kinetochore |
Networking/Round Table Discussions
| Time (UK) | |
|---|---|
| 3.30 PM | Round Table Discussions (Zoom links sent to registered participants) Networking/Posters – gather.town |
Session 2: Chair – Axonemal dyneins
| Time (UK) | Speaker | Title |
|---|---|---|
| 4.40 PM | Win Sale | Ian and Barbara Gibbons Award Introduction |
| 4.55 PM | Kai Zhang | Gibbons Lecture: Structures of outer-arm dynein array bound to microtubule doublet reveal a motor coordination mechanism |
| 5.20 PM | Hiroshi Yamaguchi | Efcab1 stabilizes the docking of outer arm dyneins onto ciliary microtubule in vertebrates. |
| 5.40 PM | Rui Zhang | High-resolution cryo-EM structures of the mechanoregulatory complexes within the axoneme |
| 6.00 PM | Poster presenters at their posters (optional) – gather.town |
September 9th
| Time (UK) | Speaker | Title |
| 1.00 PM | Poster presenters at their posters (optional) – gather.town |
Session 3: IFT transport and ciliary dynein beating
| Time (UK) | Speaker | Title |
|---|---|---|
| 2.00 PM | Jordan Mareike | In situ cryo-EM shows that IFT-dynein is transported in an inactive conformation on anterograde intraflagellar transport trains to ensure unidirectional anterograde movement in cilia |
| 2.20 PM | Aakash Mukhopadhyay | Intermediate chains assemble dynein-2 into an autoinhibited dimer to regulate intraflagellar transport |
| 2.40 PM | Noemi Zimmerman | Cryo-electron tomography revealed multiple conformations of outer arm dyneins at various stages of force generation |
| 3.00 PM | Hermes Gadelha | Dynein orchestration of the multi-scale components of mammalian sperm flagella and its implication on the 3D flagellar beating |
Networking/Round Table Discussions
| Time (UK) | |
|---|---|
| 3.30 PM | Round Table Discussions (Zoom links sent to registered participants) Networking/Posters – gather.town |
Session 4: Cell biology of dyneins
| Time (UK) | Speaker | Title |
|---|---|---|
| 4.30 PM | Jaclyn Fingerhut | mRNA localization mediates maturation of cytoplasmic cilia in Drosophila spermatogenesis |
| 4.50 PM | Addanki Triumala Nireekshit | Single molecule imaging of cytoplasmic dynein reveals the mechanism of cargo capture and motor activation |
| 5.10 PM | Aga Kendrick | Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes |
| 5.30 PM | Sydney Cason | Multiple dynein effector proteins act sequentially to drive autophagosome transport in axons |
| 5.50 PM | Kazu Oiwa | Summary and close |
| 6.10 | Poster presenters at their posters (optional) – gather.town |
Round-table discussions:
Round table discussions present an opportunity for meeting attendees to interact with junior and senior group leaders in the cytoplasmic and axonemal dynein fields (see list below). These sessions will be limited to small groups to facilitate connections with the designated table leader. Each covers a distinct theme, ranging from active research questions to career topics, but leaders and participants are encouraged to allow the discussion to develop organically in any interesting direction they choose. The round tables are particularly encouraged for junior scientists as an opportunity to meet and discuss relevant topics of interest for their future careers. When you register please select all those round tables you would be interested in attending. Slots will be filled on a first come, first serve basis and attendees will typically expect to attend one slot. The discussions will be via zoom with links sent directly to participants by email before the meeting.
Start Time: 7.30 AM Pacific Time, 9.30 AM Central Time, 10.30 AM Eastern Time, 3.30 PM UK, 4.30 PM Europe, 8.00 PM India, 11.30 PM Japan, 0.30 AM (+1 day) Australia
Wednesday 8th September
Vaishnavi Ananthanarayanan: Single Molecule Studies of Dynein
Susan Dutcher: Preassembly of Axonemal Dyneins
Erika Holzbaur: Cytoplasmic Dynein in Disease
Joe Howard: Mechanisms of ciliary beating.
Tomomi Kiyomitsu: Dynein in Mitosis
Guangshuo Ou: IFT Dynein in C. elegans
Gaia Pigino: Structural Biology of IFT
Sam Reck-Peterson: Career as an Academic Scientist
Thursday September 9th
Alan Brown and Rui Zhang: Structural Biology of Axonemes
Morgan DeSantis: Dynein Regulation
Ken’ya Furuta: Engineering Dyneins
Roop Mallik: Dynein Biophysics
Miriam Schmidts: Genetics of Human Ciliary Dynein Diseases
Thomas Surrey: In Vitro Reconstitution
Ron Vale: Career as an Academic Scientist
John Wallingford: Axonemal Dynein Assembly
Networking/Poster Sessions:
If you are not attending a round table discussion you are welcome to visit posters or join us in the Gather.town Foyer for informal discussions.
Poster presenters will submit a pdf poster (A4 size/landscape orientation) and a 5-minute video presentation. Attendees will watch at their leisure (either downloading via the meeting website or Gather.town). Participants will be able to contact poster presenter directly and set up a time to talk one-on-one. Presenters also have the opportunity to be at their posters in Gather.town for an hour before and/or after the meeting and during the Network/Poster sessions between live talks.